Non-invasive Serial Blood Collection in Guinea Pigs (Cavia porcellus)
Abstract
Blood draws from guinea pigs (Cavia porcellus) became a requirement for animals trained in several behavioral tasks pre- and postexposure to chemical warfare agents (CWAs). Due to the number of animals, the sensitivity of the behavioral assessments and the need for serial blood draws, current methods for blood collection could not be used because they required anesthesia or analgesics, extensive training, a high level of competence, and multiple technicians. The toenail clip method provided an easily trained, easily performed method of blood collection that yielded up to one milliliter of blood, required only topical anesthesia and appeared to cause little pain or stress to the animal.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2007
- Accession Number
- ADA501905
Entities
People
- Angela L. Adkins
- Anita V. Moran
Organizations
- United States Army Medical Research Institute of Chemical Defense