Evaluation of Barrier Skin Cream Effectiveness Against JP-8 Jet Fuel Absorption and Irritation

Abstract

The DoD and Air Force use large volumes of JP-8 annually. Due to the irritation produced by JP-8, the objective of this study was to obtain, formulate and experimentally select the most effective augmentation cream or lotion to inhibit skin exposure to liquid JP-8 during handling or after spills. Creams were tested first in vitro using cell diffusion chambers and then using the New Zealand White Rabbit model. Over-the-counter creams were first tested to evaluate the proof of concept of preventing dermal irritation with a barrier cream. Finally, formulated barrier creams were developed by two different companies and tested in-house. An effective barrier cream was not found using the rabbit model. The most effective protection against JP-8 remains personal protective equipment including gloves, and etc.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2009
Accession Number
ADA503802

Entities

People

  • Aaron J. Guilfoil
  • David R. Mattie
  • Gayle L. Siegel
  • James A. Benjack
  • Latayo N. Talton
  • Michael J. Wagner
  • Richard J. Godfrey
  • Sean C. Stevens
  • Teresa R Sterner

Tags

Communities of Interest

  • Biomedical
  • Ground and Sea Platforms

DTIC Thesaurus Topics

  • Air Force
  • Air Force Research Laboratories
  • Biological Sciences
  • Biotechnology
  • Chemical Warfare
  • Chemical Warfare Agents
  • Fuels
  • Jet Engine Fuels
  • Laboratory Animals
  • Materials
  • Medical Personnel
  • New Zealand
  • Personal Protective Equipment
  • Protective Equipment
  • Skin Diseases
  • Tissues
  • Turbines

Fields of Study

  • Agricultural and Food sciences

Readers

  • Materials Science
  • Petroleum Engineering
  • Toxicology/Environmental Toxicology