Enhancing Quality of Life for Breast Cancer Patients with Bone Metastases

Abstract

Current treatment for osteolytic breast cancer bone metastasis typically involves radiation therapy (RTX) to palliate bone pain and a bisphosphonate to inhibit osteoclastic bone resorption. The goal of this research was to determine the effects of zoledronic acid as an adjunct to RTX on restoring bone strength and density. We also investigated whether the combination of ZA and an anabolic agent (parathyroid hormone, PTH) as adjuncts to RTX further enhanced bone strength and thus decrease the risk of subsequent pathological fractures.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2008
Accession Number
ADA504964

Entities

People

  • Sarah A. Arrington

Organizations

  • Syracuse University

Tags

DTIC Thesaurus Topics

  • Bone And Bones
  • Bone Diseases
  • Breast Cancer
  • Cell Physiological Processes
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Health Services
  • Medical Personnel
  • Neoplasms
  • Orthopedic Surgical Procedures
  • Orthopedics
  • Osteoporosis
  • Test Methods
  • X-Ray Computed Tomography

Fields of Study

  • Medicine

Readers

  • Immunology and Pathology
  • Oncology (Cancer Research).