Incorporating Functional Imaging Information into rpFNA Analysis for Breast Cancer Detection in High Risk Women

Abstract

The overall goal of this work is to correlate the imaging information from the dual-modality, dedicated single photon emission computed tomography (SPECT) and computed tomography device with the results of random periareolar fine needle aspiration (rpFNA) in women at high risk for breast cancer. To maximize the information gained from this collaborative study, the whole breast will be imaged prior to rpFNA and the needles will be imaged after aspiration has been collected. In this first year of work, efforts have been concentrated on understanding the SPECT image signal and correcting for artifacts, attenuation and scatter to the reconstructed SPECT images. Additionally, preliminary data was collected to investigate the potential of imaging the radioactive rpFNA needles with our current SPECT camera. Other aspects of the training program have been initiated, including attending local and international conferences, shadowing breast cancer related procedures in the hospital, and drafting papers for peer review.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 2009
Accession Number
ADA505049

Entities

People

  • Kristy L. Perez

Organizations

  • Duke University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acquisition
  • Artifacts
  • Attenuation
  • Breast Cancer
  • Data Sets
  • Detection
  • Detectors
  • Diagnostic Imaging
  • Health Services
  • Institutional Review Board
  • Medical Personnel
  • Neoplasms
  • Nuclear Medicine
  • Operating Systems
  • Radiology
  • Tomography
  • X-Ray Computed Tomography

Fields of Study

  • Medicine
  • Physics

Readers

  • Medical Imaging.
  • Oncology and Biomarker-Based Cancer Detection.