Development of a Portable DNA Sensor System

Abstract

A fully-integrated, palmtop, field-portable DNA analyzer that is capable of responding within 30 minutes to a sample of as little as three strands of DNA will enhance the survivability of the warfighter. This technology has been sponsored through the Institute of Collaborative Biotechnologies and was lead by Nanex LLC with co-investigators from the US Army Research Laboratory and the University of California, Santa Barbara. This analyzer will not sacrifice selectivity or operational convenience. Reliable, high-speed detection of DNA will provide broad support in many Army missions. This project will transition findings and breakthroughs derived from UARC basic research programs to a device that can Detect to Protect by performing environmental sampling for biological threats. The analyzer will be able to monitor indigenous foods supplied to deployed troops by detecting inherent or intentional contaminants including native microorganisms, typical food-borne pathogens and biowarfare agents. As more is learned about physical changes during infection, it can Detect to Treat through use in medical diagnostics. Current technology informs soldiers when to take a protective posture against chemical threats. This sensor will provide an analogous technology for biological threats. The potential functionality, low cost, ruggedness, ease of use and portability of this analyzer will encourage broad deployment and use, greatly enhancing the safety of troops in times of peace and at war.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 2008
Accession Number
ADA505930

Entities

People

  • C. D. Meinhart
  • H. T. Soh
  • J. J. Sumner
  • K. W. Plaxco
  • P. Freudenthal

Organizations

  • United States Army Research Laboratory

Tags

Communities of Interest

  • Biomedical
  • Sensors

DTIC Thesaurus Topics

  • Abstracts
  • Analyzers
  • Biotechnology
  • Blood
  • Detection
  • Detectors
  • Dna Biosensors
  • Electron Transfer
  • Electronics
  • Elements
  • Fabrication
  • Field Programmable Gate Arrays
  • Military Research
  • Personal Digital Assistants
  • Self Assembled Monolayers
  • Shelf Life
  • Standards

Readers

  • Computer Science/Computer Engineering/Data Science/Digital Signal Processing.
  • Maritime Combat Support and Expeditionary Logistics.
  • Research Science/Academic Research

Technology Areas

  • Biotechnology