Alkylating Derivatives of Vitamin D Hormone for Prostate Cancer

Abstract

The two most significant achievements in this reporting period are : launching of studies to evaluate the molecular mechanism/s of action of . 1,25-dihydroxyvitamin D3-3-bromoacetate (1,25(OH)2D3-3-BE), and development of an androgen-sensitive mouse model of human prostate cancer. In addition we have screened several cancer cell lines to determine potential efficacy of 1,25(OH)2D3-3-BE in cancers, in addition to prostate cancer.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2008
Accession Number
ADA506555

Entities

People

  • Rahul Ray

Organizations

  • Boston University

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Alcohols
  • Androgens
  • Animals
  • Biomedical Research
  • Body Weight
  • Cell Line
  • Cell Physiological Processes
  • Cells
  • Chemical Compounds
  • Detectors
  • Hormones
  • Neoplasms
  • Prostate
  • Prostate Cancer
  • Radioactivity
  • Vitamin D

Readers

  • Oncology (Cancer Research).
  • Prostate Cancer Biology.