A Comparative Analysis of Toxicity Models
Abstract
Four toxicity models are compared to asses the significance of using different toxicity models for military medical planning. The four models examined are Haber's law, the integrated toxic load model, the mean concentration toxic load model, and a two-compartment toxico-kinetic model. All of these models are applied to the same hypothetical attack scenario and the personnel exposed in the attack are classified into categories according to casualty status and injury severity. For this scenario, Haber's law was found to predict the greatest number of casualties, while the mean concentration toxic load model predicted the fewest, 32% fewer than Haber's Law. The integrated toxic load model and the two-compartment toxico-kinetic model predicted the same number of casualties for the scenario investigated. A discussion of the resulting casualty estimates provides insight into the conditions under which the different models may lead to different results.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 2008
- Accession Number
- ADA506567
Entities
People
- Alison E. Lawrence
- Jeffrey H. Grotte
- Julia K. Burr
- Lucas L. Laviolet
- Scott L. Weinrich
Organizations
- Institute for Defense Analyses