Inclusion of Minority Patients in Breast Cancer Clinical Trials: The Role of the Clinical Trial Environment

Abstract

Clinical trials are the primary vehicle for transforming laboratory discoveries in breast cancer care into clinical practice. Enhanced participation by minorities in these trials is necessary to assess the effectiveness of advances in breast cancer care among major subpopulations and to ensure equity in the distribution of research benefits. However, minority participation in clinical trials will likely remain low without research designed to understand the reasons for limited participation. To address persistent ethnic and socioeconomic disparities in cancer care, including participation in research, interventions need to assess the broader context of clinical trials and include the larger community where these trials take place. Our study examines the combined effect of these factors on minority referral. The research team has completed all key research activities: identifying all active breast cancer clinical trials in the four states (CA, FL, IL and NY), identifying clinical trial research team members, obtaining datasets for key community indicators, identifying all breast cancer physicians, refining the data for preliminary analysis, finalizing all survey instruments, and completing physician surveys for all four states and the RTM surveys for California.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 2009
Accession Number
ADA509888

Entities

People

  • Celia P. Kaplan

Organizations

  • University of California, San Francisco

Tags

DTIC Thesaurus Topics

  • Asian Americans
  • Biomedical Research
  • Breast Cancer
  • California
  • Clinical Trials
  • Communities
  • Data Analysis
  • Databases
  • Ethnic Groups
  • Health Care
  • Indicators
  • Medical Personnel
  • Minority Groups
  • Neoplasms
  • New York
  • Physicians
  • Urban Areas

Fields of Study

  • Medicine

Readers

  • Breast cancer cell signaling and growth regulation.
  • Clinical Trial Research.
  • Organizational Psychology.