Multiadaptive Plan (MAP) IMRT to Accommodate Independent Movement of the Prostate and Pelvic Lymph Nodes

Abstract

We found that the direct image based and contour based alignment methods are both reliable to detect translational setup errors for patients with prostate cancer. In the longitudinal direction, the measurement uncertainties are slightly increased with the direct image alignment method when compared to the contour alignment method. Since the manual adjustments are necessary with the both alignment methods, the results of this study may subject to inter-observer variations. Further study will investigate the effect of inter-observer variations between the two methods. With a proof of principle study, we found that the multiple adaptive plan (MAP) approach is a clinically feasible strategy. Verification plans calculated with daily MV-CBCT can further provide patient specific dose guidance.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 2009
Accession Number
ADA511267

Entities

People

  • Ping Xia

Organizations

  • University of California, San Francisco

Tags

DTIC Thesaurus Topics

  • Algorithms
  • Anatomy
  • Biomedical Research
  • Cancer
  • Computer Programs
  • Computers
  • Guidance
  • Image Registration
  • Linear Accelerators
  • Measurement
  • Neoplasms
  • Oncology
  • Prostate
  • Prostate Cancer
  • Radiation Oncology
  • Radiotherapy
  • Tissues

Fields of Study

  • Medicine
  • Physics

Readers

  • Computer Vision.
  • Medical Imaging.
  • Regression Analysis.