Towards Complex Abiotic Systems for Chemical and Biological Sensing
Abstract
There have been at least two decades of research focused on developing biosensors, which mimic human physiological responses, but most of the work has attempted to couple living cells, their receptors, and even scaffolded tissues to optical or electronic sensors. All these biosensors had limitations imposed upon them by living systems. They required extensive life support and had very limited shelf life. Advances in synthetic biology, materials science, molecular engineering, and information technology have demonstrated the potential to create completely synthetic "abiotic" systems, which can be programmed to possess the sense, response, and adaptation capabilities of living systems. This report reviews the state of the art and suggests an approach to the design of abiotic systems for chemical and biological defense.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 2009
- Accession Number
- ADA511394
Entities
People
- Donna M. Hoffman
- Erica R. Valdes
- James J. Valdes
Organizations
- Edgewood Chemical Biological Center