Effect of Skin Abrasions on the Efficacy of the Repellent Deet Against Aedes Aegypti

Abstract

Abrasion of repellent-treated human skin affected the efficacy of a sustained-release insect repellent containing N,N-diethyl-3-methylbenzamide (deet) against bites of Aedes aegypti. Skin treated with repellent when abraded up to 30 times showed significantly lower protection than unabraded skin against mosquito bites for 10 h. The mean value of the kinetic coefficient of friction during skin abrasion by clothing (battle dress uniform fabric) for repellent-treated skin (0.159 +/- 0.003) was significantly higher than untreated skin (0.122 +/- 0.005). Repellent-treated skin appeared stickier than the untreated skin. An increase in the number of skin abrasions by clothing resulted in a reduced duration of protection against mosquito bites.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1998
Accession Number
ADA512520

Entities

People

  • Leopoldo M. Rueda
  • Louis C. Rutledge
  • Raj K. Gupta

Organizations

  • Walter Reed Army Institute of Research

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abrasion
  • Abstracts
  • Allergy And Immunology
  • Coefficients
  • Diseases And Disorders
  • Entomology
  • Evaporation
  • Fabrics
  • Friction
  • Insect Repellents
  • Insects
  • Lubrication
  • Materials
  • Resistance
  • Skin Friction
  • Sweating
  • Test Methods

Readers

  • Toxicology/Environmental Toxicology
  • Vector-Borne Disease and Entomology