Cord Blood Stem Cell Procurement in Minority Donors
Abstract
This is the final report summarizing all of the activity and ongoing activity. The funding of this project has now created a consortium of robust collection sites that will be focused on the procurement of high quality cord blood units (CBU) for stem cell transplantation. The educational process and expansion of collection sites has given us a steady supply of cord blood for clinical use; and now we have the operational nucleus of several collection sites that is self-perpetuating a continual drive to expand to affiliated institutions. The greatest benefit of this project is the demonstration of how we solved the problem of increasing the overall yield of the cord blood units. We convincingly demonstrate that putting resources into individual patient education and prenatal visits is not likely to increase the cell yield and thus will not likely increase the number of bankable cord blood units for transplantation. With these findings, we then initiated a program of educating the birth-care providers and public in several newly recruited institutions and we are now able to collect increasing high-quality cord blood units. Furthermore, we have also implemented a quality improvement program within the institution. We have data to show that through direct feedback to the birth-care providers of their performance in procuring high-quality units, we were able to improve the yield for each birth-care provider. Finally, we extend the observation of transplant outcomes of the African/American CBU recipients compared with other racial groups at Karmanos Cancer Center.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 2009
- Accession Number
- ADA513067
Entities
People
- Voravit Ratanatharathorn
Organizations
- Wayne State University