Department of Defense Era of Hope Scholar Award "Nanotechnology-Enabled Optical Molecular Imaging of Breast Cancer"
Abstract
This project focuses on development of nanotechnology-enabled optical molecular imaging technologies for applications in both breast cancer diagnosis and monitoring therapeutic response. The project consists of two major efforts: (1) optical instrumentation technology development and (2) development of complementary engineered nanomaterials for use in conjunction with the instrumentation created to provide molecular specificity. A particularly significant effort is underway to develop needle-compatible fiber optic probes to enable in vivo imaging of tumors with micron resolution in order to provide a new microscopic, high resolution imaging modality to complement the low resolution, macroscopic imaging modalities already in common clinical use. Over the first two years of this effort, a first and second generation needle-compatible fiber optic probe system have been developed as have new methods for synthesis and bioconjugation of shaped and layered gold nanoparticle imaging agents and cadmium-free luminescent quantum dots.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2009
- Accession Number
- ADA513184
Entities
People
- Rebekah Drezek
Organizations
- Rice University