Field Evaluation of Deet and a Piperidine Repellent Against Aedes communis (Diptera: Culicidae) and Simulium venustum (Diptera: Simuliidae) in the Adirondack Mountains of New York
Abstract
Repellent efficacy of N,N-diethyl-3-methyl-benzamide (deet), the piperidine, 1-[3-cyclohexen-1-ylcarbonyl]-2-methlypiperidine (AI3-37220), and a 1:1 ratio of deet + AI3-37220 were evaluated topically (0.25 mg/cm2 applied in ethanol solution) on human volunteers against the mosquito Aedes communis (DeGreer) and the black fly Simulium venustum Say. The average repellency of all three formulations was >95% at 4 h. For both mosquitoes and black flies, deet along provided <90% protection at 6 h, whereas AI3-37220 provided >95% protection. Although repellent treatments were not significantly different overall, the contrasts between AI3-37220 versus deet were significant at 6 and 8 h. The 95% confidence interval on percent repellency at 6 h ranged from 90.1 to 98.9% for AI3-37220 versus 64.3 to 82.2% for deet, and at 8 h ranged 76.1 to 88.5% for AI3-37220 versus 47.8 to 64.0% for deet. Similarly, the confidence interval for protection against black flies at 6 h by AI3-37220 ranged from 86.3 to 99.5% and did not overlap with the confidence interval provided by deet along (51.2 to 78.8%). There was no evidence of synergistic repellency from a combination of the two compounds; i.e., protection from combined compounds was no better than either repellent used alone.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 2000
- Accession Number
- ADA513306
Entities
People
- Claudia Golenda
- Daniel Strickman
- Kenneth R. Mcpherson
- Lisa Keep
- Mustapha Debboun
- Richard Charles Wilkerson
- Robert A. Wirtz
- Robert Burge
- Terry A. Klein
- Victoria B. Solberg
Organizations
- Walter Reed Army Institute of Research