Drug Targets in Infections With Ebola and Marburg Viruses

Abstract

The development of antiviral drugs for Ebola and Marburg viruses has been slow. To date, beyond supportive care, no effective treatments, prophylactic measures, therapies or vaccines are approved to treat or prevent filovirus infections. In this review, we examine the current treatments available to administer care for filovirus infection, the potential therapeutic targets that can be used for filovirus drug development, and the various drug targeting techniques used against filoviruses.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2009
Accession Number
ADA513361

Entities

People

  • Biggins E. Julia
  • Geisbert W. Thomas
  • Hensley E. Lisa
  • Melanson R. Vanessa
  • Olinger G. Gene
  • Wahl-jensen Victoria

Organizations

  • United States Army Medical Research Institute of Infectious Diseases

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Adaptive Immunity
  • Blood
  • Cell Physiological Processes
  • Cells
  • Chemistry
  • Diseases And Disorders
  • Hematologic Diseases
  • Infection
  • Lymphocytes
  • Marburg Virus
  • Medical Personnel
  • Peptides
  • Proteins
  • Rodents
  • Sepsis
  • Virus Diseases
  • Viruses

Fields of Study

  • Biology
  • Medicine

Readers

  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.
  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech