Enzyme-Mediated Assimilation of DNA-Functionalized Single-Walled Carbon Nanotubes
Abstract
When pyrimidine-functionalized carbon nanotubes were incubated with single-stranded DNA ligase, formations of macroscopic aggregates were observed. Wet-cell transmission electron microscopy imaging revealed that the nanotubes were radially bound to form a 3D latticelike structure. These structures were not observed in control reactions lacking ligase or adenosine triphosphate. Raman spectroscopy analysis revealed no spectra indicative of carbon nanotubes in ligase-unamended controls; however, spectra were observed in radial breathing mode and in the G and G' bands in reactions containing ligase. Furthermore, the addition of deoxyribonuclease to the ligated reactions dispersed the aggregates, and a reduction in Raman spectral intensity was observed.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 2010
- Accession Number
- ADA513373
Entities
People
- Charles P. Marsh
- Charles R. Welch
- Clint M. Arnett
- Jae-hee Han
- Jeffry H. Gray
- Michael Strano
- Thomas A. Carlson
Organizations
- Engineer Research and Development Center