Functional Voice Outcomes After Thyroidectomy: An Assessment of the Dsyphonia Severity Index (DSI) After Thyroidectomy

Abstract

The Dysphonia Severity Index (DSI) is an objective multiparametric acoustic calculation of vocal function; however, its changes after thyroidectomy have not yet been described. Patient-reported symptoms, as well as auditory perceptual, acoustic, and videolaryngostroboscopic (VLS) data, were collected prospectively before and after thyroidectomy. Voice outcomes (normal versus negative voice outcome [NVO]) at 6 months after thyroidectomy were based on a combination of voice symptoms and objective findings. The DSI was assessed over the perioperative course, and differences were determined with Wilcoxon signed rank tests. The DSI was compared between study groups (normal versus NVO) using t tests, analyses of variance (ANOVAs), or rank sum tests as appropriate. The predictive value of DSI for long-term voice dysfunction was assessed by an area under the receiver operating characteristics curve analysis. Correlations between DSI and Consensus Auditory Perceptual Ratings of Voice (CAPE-V) and the patient reported Voice Handicap Index (VHI) were determined with Pearson's correlation coefficients. In all, 62 patients were evaluated before, 1--4 weeks after, and 6 months after thyroidectomy. Eight (13%) patients were diagnosed with NVO at 6 months. The DSI was different postoperatively between NVO and normal voice (P = .005, repeated measures [RM]-ANOVA), with the NVO group demonstrating a lesser DSI value and greater change from pre-operative assessment at the first postoperative visit when compared with the normal group (P < .006 each). The DSI differed significantly for pre-operative and 6-month assessments according to sex, smoking status, and age. Short-term postoperative DSI (area under the curve [AUC] = 0.795) and DSI change from baseline to 1--4 weeks (AUC = 0.835) were highly predictive of 6-month NVO.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2010
Accession Number
ADA514171

Entities

People

  • Alexander Stojadinovic
  • George Coppit
  • Joyce Gurevich-uvena
  • Leah B. Helou
  • Leonard R. Henry
  • Nancy Pearl Solomon
  • Robin S. Howard

Organizations

  • Walter Reed National Military Medical Center

Tags

DTIC Thesaurus Topics

  • Autonomic Nervous System
  • Data Science
  • Databases
  • Diseases And Disorders
  • Dysfunction
  • Health Services
  • Information Science
  • Laryngeal Diseases
  • Light Sources
  • Loudness
  • Medical Personnel
  • Physicians
  • Quality Of Life
  • Statistical Analysis
  • Surgery
  • Test And Evaluation
  • Thyroidectomy

Fields of Study

  • Medicine

Readers

  • Neurotrauma and Rehabilitation Medicine.
  • Regression Analysis.
  • Speech Processing/Speech Recognition.