Biocompatible and Biomimetic Self-Assembly of Functional Nanostructures

Abstract

We have discovered and continue to explore a unique metabolically and optically controlled lithography approach that allows patterned integration of live cells into nominally solid-state devices and maintains their viability under extreme conditions of desiccation and starvation. We used our cellular integration approach to explore quorum sensing at the individual cell level. We have also developed techniques for the integration of mammalian cells into devices. We continue to create biocompatible cellular microenvironments with tailored chemical and physical properties that direct cellular behavior. In summary our research provides a means to integrate cells into devices and platforms, maintain their viability under harsh conditions, and direct their behavior thorough engineered microenvironments.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Feb 28, 2010
Accession Number
ADA515431

Entities

People

  • C. J. Brinker
  • Eric C. Carnes

Organizations

  • University of New Mexico

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Cell Physiological Processes
  • Cells
  • Cellular Structures
  • Chemical Synthesis
  • Chemistry
  • Composite Materials
  • Confocal Microscopy
  • Fungi
  • Genetic Engineering
  • Materials
  • Materials Laboratories
  • Materials Processing
  • Materials Science
  • Nanocomposites
  • Nanotechnology
  • Self Assembly
  • Three Dimensional

Fields of Study

  • Biology

Readers

  • Microbial Pathology
  • Nanocomposite Materials Science

Technology Areas

  • Biotechnology
  • Microelectronics