Toxicity of Trinitrotoluene to Sheepshead Minnows in Water Exposures

Abstract

Lethal effects of trinitrotoluene (TNT) to juvenile sheepshead minnows (JSHM) (Cyprinodon variegatus) were assessed in ten-day water exposures. Ten-day median lethal concentrations (LC50s) were 2.3 and 2.5 mg/L, the 10-d median lethal residue value (LR50) was 26.1 micromol/kg wet weight (ww), and bioconcentration factors (BCFs) ranged from 0.7 to 2.4 L/kg. The lethal effects of TNT and its transformation products 2-aminodinitrotoluene (2-ADNT), 2,4-diaminonitrotoluene (2,4-DANT) and trinitrobenzene (TNB) to JSHM were compared in 5-d static-renewal exposures. Nitroreduction decreased the toxicity of TNT to SHM, as the 5-d LC50 for 2-ADNT was 8.6 mg/L and the lowest lethal concentration of 2,4-DANT was 50.3 mg/L. TNB (5-d LC50=1.2 mg/L) was more toxic than TNT to SHM. The 5-d LR50s were 4.3 mg/kg ww (20.4 micromol/kg) for SumTNT (TNT exposure) and 54.2 mg/kg ww (275.3 mmol/kg) for 2-ADNT and significant mortality occurred at 47.4 mg/kg ww (283.6 micromol/kg). The range of BCF values was from 1.8 to 2.4, 5.6 to 8.0, and 0.6 to 0.9 L/kg for TNT, 2-ADNT, and 2,4-DANT, respectively.

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Document Details

Document Type
Technical Report
Publication Date
Feb 06, 2010
Accession Number
ADA515578

Entities

People

  • Alfreda B. Gibson
  • Guilherme R Lotufo
  • William M. Blackburn

Organizations

  • Engineer Research and Development Center

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Aquatic Organisms
  • Chemical Analysis
  • Chemistry
  • Ecotoxicology
  • Environment
  • Environmental Protection
  • Explosives
  • Fish
  • Liquid Chromatography
  • Munitions
  • Three Dimensional
  • Toxicity
  • Unexploded Ammunition

Fields of Study

  • Environmental science

Readers

  • Agricultural Chemistry/Soil Science
  • Aquatic Ecology