X-Ray Phase Imaging For Breast Cancer Detection
Abstract
The long term objective of the project is to develop a low-dose and quantitative phase x-ray imaging technique for facilitating breast cancer detection. Phase retrieval from a single phase contrast image is the key strategy for this project. In this period we have accomplished following tasks: (1) Successfully developed a new phase retrieval method with a full account of the nonlinear Fresnel propagators. This new phase retrieval method provides the scientific foundation and framework for developing new and more accurate phase retrieval algorithms for this project. (2) Conducted the system design study for the project. Importantly we have determined the optimal imaging geometry based on the quantitative phase contrast visibility analysis. (3) Conducted system hardware integration. A prototype is developed and the tests showed that the prototype is well functioning for phase contrast image acquisition. In the coming year we will conduct phase imaging experiments with custom-made breast phantoms. Especially we will incorporate the measured source incoherence effects and CR-detector response effects into the phase retrieval algorithms for accurately reconstruction of the maps of projected electron densities of the phantoms.
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 2009
- Accession Number
- ADA516472
Entities
People
- Xizeng Wu
Organizations
- University of Alabama