Use of Exogenous Progestins and Risk or In Situ and Invasive Breast Cancer

Abstract

Given the large number of women exposed to progestins through either contraceptives or menopausal hormone therapies, clarifying the etiologic role of progestin in relation to breast cancer is of public health importance. This study's two projects will further our understanding of the potential risk of breast cancer associated with progestin use. Project 1 involves the enrollment of 225 in situ breast cancer cases 20-44 years of age. Project 2 is a case-control study of women 55-74 years of age that will enroll 435 controls and 870 breast cancer cases (with three different histologic types of breast cancer, including 435 ductal cases and 435 lobular and mixed cases). Both projects involve a detailed in-person interview and review and testing of tumor samples for various tumor markers. There are no major findings from this study yet as data collection is currently in progress for both projects.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2009
Accession Number
ADA516616

Entities

People

  • Christopher Li
  • Janet Daling
  • Kathleen Malone
  • Peggy Porter

Organizations

  • Fred Hutchinson Cancer Center

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Breast Cancer
  • Carcinoma
  • Data Analysis
  • Department Of Defense
  • Health
  • Health Services
  • Institutional Review Board
  • Medical Personnel
  • Neoplasms
  • Physicians
  • Public Health
  • Questionnaires
  • Reproductive Control Agents
  • Therapy

Fields of Study

  • Medicine

Readers

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