Capillary Inlet Concentrator for the Integrated Virus Detection System (IVDS)

Abstract

The standard method for concentration of virus samples with the Integrated Vims Detection System (IVDS) is to use a tangential flow filtration system to reduce the volume of the sample, while removing impurities such as salts and small cellular debris. This report investigated the IVDS' ability to concentrate the virus sample as well as remove impurities with a filtration attachment on the inlet side of the electrospray module. The filtration attachment or concentrator allowed the virus sample to be purified and concentrated and then analyzed with the IVDS without removing the sample from the IVDS.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Mar 01, 2010
Accession Number
ADA516728

Entities

People

  • Charles H. Wick
  • Patrick E. Mccubbin

Organizations

  • Edgewood Chemical Biological Center

Tags

Communities of Interest

  • Counter WMD

DTIC Thesaurus Topics

  • Attachment
  • Biological Factors
  • Department Of Defense
  • Detection
  • Electrospray
  • Engineering
  • Filters
  • Filtration
  • Impurities
  • Information Operations
  • Microvessels
  • Military Research
  • Molecular Weight
  • Particles
  • Standards
  • Technical Information Centers
  • Viruses

Readers

  • Analytical Chemistry
  • Software Engineering
  • Virology (or Medical Virology).