Photonic Breast Tomography and Tumor Aggressiveness Assessment

Abstract

The tasks performed and the progresses made during the second year include: (a) pursuing planned training objectives of the CCNY researchers through laboratory rotations at the Memorial Sloan Kettering Cancer Center (MSKCC); and (b) conducting research on development of non-invasive optical imaging and spectroscopic approaches for breast tumor detection. The CCNY researchers received training on (i) small animal handling; (ii) Cell culture, bioluminescence assay and imaging; (iii) Western Blotting and Flow Cytometry; (iv) small animal imaging techniques; and (v) magnetic resonance imaging and spectroscopy. They also attended group meetings and seminars to develop sound background in the biological and clinical aspects of cancer research. The research component involved development of numerical algorithms based on time reversal matrix method and principal component analysis, and using those along with a method based on independent component analysis for locating tumors in a model cancerous breast assembled using ex vivo breast tissue specimens, and targets in breast simulating model media.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2009
Accession Number
ADA517344

Entities

People

  • F.b. Lin
  • J.a. Koutcher
  • R.r. Alfano
  • S.k. Gayen

Organizations

  • New York University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acquisition
  • Algorithms
  • Bioluminescence
  • Biomedical Research
  • Breast Cancer
  • Cancer
  • Culture Techniques
  • Detection
  • Detectors
  • Factor Analysis
  • Magnetic Resonance
  • Magnetic Resonance Imaging
  • Spectroscopy
  • Three Dimensional
  • Tomography
  • Training
  • X-Ray Computed Tomography

Fields of Study

  • Physics

Readers

  • Oncology (Cancer Research).
  • Oncology and Biomarker-Based Cancer Detection.
  • Research Science/Academic Research