Structural and Functional Analysis of CA125: Potential for Early Diagnosis and Understanding the Immune Evasion Strategies of Epithelial Ovarian Tumors

Abstract

The proposed studies will define the structure and the biological function of the epithelial ovarian tumor marker MUC16 (CA125). The knowledge obtained can be utilized to develop better diagnostic tests for early detection of ovarian cancer and also to understand the pathogenesis of this disease. Due to delays in procuring the appropriate approvals from the Institutional Review Boards we have not been able to initiate the proposed studies. We therefore do not have any major findings/accomplishments to report at this time.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2005
Accession Number
ADA517680

Entities

People

  • Manish S Patankar

Organizations

  • University of Wisconsin–Madison

Tags

DTIC Thesaurus Topics

  • Amniotic Fluid
  • Biomedical Research
  • Cancer
  • Cells
  • Cultured Cells
  • Department Of Defense
  • Diseases And Disorders
  • Electronic Mail
  • Functional Analysis
  • Institutional Review Board
  • Lymphocytes
  • Molecular Weight
  • Neoplasms
  • Ovarian Cancer
  • Pathogenesis
  • Scientific Research

Readers

  • Oncology
  • Oncology and Biomarker-Based Cancer Detection.