Molecular Modeling Studies of Fluorinated Peptide and Amino Acid Analogs
Abstract
The specific aims of this work are the study of fluorinated peptide mimetics and fluorinated amino acids. NARC funding in the amount of 12.5 days was provided in support of this work during the Summer of 2007. This time was roughly equally divided between continuing work on the hydrogen bonded dimer complexes of fluoroalkene model compounds (fluoroethylene and 2- fluoro-2-butene) and beginning preliminary studies of fluorinated and hydroxylated amides as models for peptidomimetics. The details of these studies and how they fit into the larger context of the entire research program can be found in the detailed proposal (Enclosure (1)). A synopsis of the key results found during the support time is presented below.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 2007
- Accession Number
- ADA519680
Entities
People
- Joseph Urban