Recommendation of an Occupational Exposure Level for Perfluro-N-Butyl Iodide

Abstract

Perfluoro-n-butyl iodide (PFBI) is a promising alternative to chlorofluorocarbon solvents used in aircraft ground maintenance operations and other military and commercial operations, because it cleans well, has zero ozone depletion potential and has extremely low global warming properties. The purpose of this technical report was to summarize the toxicity profile of PFBI and propose an occupational exposure level (OEL) for PFBI. Toxicity tests were performed with PFBI to determine and evaluate its health hazard. Results of these investigations were summarized, and lowest-observed-adverse-effect-levels (LOAELs) and no-observed-adverse-effect-levels (NOAELs) were identified. Dosimetric adjustments for daily exposure time and uncertainty factors were selected, discussed, and applied to provide a basis for the proposed OEL. For acute (single event) exposure, a ceiling OEL of 3,900 ppm PFBI was proposed. For repeated exposure, an 8-hr time weighted average of 40 ppm PFBI was proposed.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2006
Accession Number
ADA521405

Entities

People

  • Darol E. Dodd
  • David R. Mattie
  • Gary M. Hoffman
  • Peter J. John

Organizations

  • Air Force Research Laboratory

Tags

DTIC Thesaurus Topics

  • Air Force
  • Air Force Research Laboratories
  • Biological Sciences
  • Biotechnology
  • Blood
  • Body Weight
  • Chemical Synthesis
  • Chemistry
  • Endocrine Glands
  • Environment
  • Environmental Protection
  • Governments
  • Health Services
  • Hormones
  • Nose
  • Thyroid Hormones
  • Toxicity

Fields of Study

  • Environmental science

Readers

  • Auditory Neuroscience/Auditory Physiology.
  • Environmental Engineering.
  • Environmental Impact Assessment (EIA) of Proposed Air Force Base Actions.