Tetracycline Susceptibility Testing and Resistance Genes in Isolates of Acinetobacter baumannii-Acinetobacter calcoaceticus Complex from a U.S. Military Hospital

Abstract

Infections with multidrug-resistant Acinetobacter baumannii-Acinetobacter calcoaceticus complex bacteria complicate the care of U.S. military personnel and civilians worldwide. One hundred thirty-three isolates from 89 patients at our facility during 2006 and 2007 were tested by disk diffusion, Etest, and broth microdilution for susceptibility to tetracycline, doxycycline, minocycline, and tigecycline. Minocycline was the most active in vitro, with 90% of the isolates tested susceptible. Susceptibilities varied significantly with the testing method. The acquired tetracycline resistance genes tetA, tetB, and tetA(39) were present in the isolates.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2009
Accession Number
ADA522596

Entities

People

  • Clinton K. Murray
  • Duane R. Hospenthal
  • Heather C. Yun
  • Katrin Mende
  • Kevin S. Akers
  • Miriam L. Beckius
  • Xin Yu

Tags

DTIC Thesaurus Topics

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Bacteria
  • Health Care
  • Health Services
  • Hospitals
  • Infection
  • Medical Personnel
  • Military Hospitals
  • Military Medicine
  • Military Operations
  • Military Personnel
  • Resistance
  • Test Methods
  • Wound Infections
  • Wounds And Injuries

Readers

  • Military/Explosive Ordnance Disposal (EOD) Technology
  • Trauma or Military Medicine