Reaction of Chlorosulfonyl Isocyanate (CSI) with Fluorosubstituted Alkenes: Evidence of a Concerted Pathway for Reaction of CSI with Fluorosubstituted Alkenes (Preprint)
Abstract
Concerted reactions are indicated for the electrophilic addition of chlorosulfonyl isocyanate with monofluoroalkenes. A vinyl fluorine atom on an alkene raises the energy of a step-wise transition state more than the energy of the competing concerted pathway. This energy shift induces CSI to react with monofluoroalkenes by a one-step process. The low reactivity of CSI with monofluoroalkenes, stereospecific reactions, the absence of 2:1 uracil products with neat fluoroalkenes and quantum chemical calculations support a concerted pathway.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 2010
- Accession Number
- ADA523002
Entities
People
- Arnold L. Reingold
- Chris E. Moore
- Dale Shellhamer
- Danielle M. Hassler
- David J. Vandenbroek
- Jacob J. Thorpe
- Jerry A. Boatz
- Kelli R. Hickle
- Kevyn J. Davenport
- Victor L. Heasley
Organizations
- Air Force Research Laboratory