A High-Throughput Pipeline for the Design of Real-Time PCR Signatures

Abstract

Pathogen diagnostic assays based on polymerase chain reaction (PCR) technology provide high sensitivity and specificity. However, the design of these diagnostic assays is computationally intensive, requiring high-throughput methods to identify unique PCR signatures in the presence of an ever increasing availability of sequenced genomes.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jun 23, 2010
Accession Number
ADA523444

Entities

People

  • Jaques Reifman
  • Kamal Kumar
  • Nela Zavaljevski
  • Ravi V. Satya

Tags

DTIC Thesaurus Topics

  • Application Software
  • Availability
  • Biomedical Research
  • Biotechnology
  • Chain Reactions
  • Chemical Reactions
  • Computational Biology
  • Department Of Defense
  • Design Criteria
  • High Performance Computing
  • Infectious Diseases
  • Operating Systems
  • Pathogenic Bacteria
  • Pipelines
  • Polymerase Chain Reaction
  • Thermodynamic Properties
  • Throughput

Fields of Study

  • Biology

Readers

  • Adaptive Control and Estimation with Uncertainty in Dynamic Systems.
  • Molecular Genetics