Incorporating Functional Imaging Information into rpFNA Analysis for Breast Cancer Detection in High Risk Women
Abstract
The overall goal of this work is to correlate the imaging information from the dual-modality, dedicated single photon emission computed tomography (SPECT) and computed tomography device with the results of random periareolar fine needle aspiration (rpFNA) in women at high risk for breast cancer. In this second year of work, efforts have been concentrated on quantifying the SPECT image signal by correctly modeling the physics in the reconstruction code including attenuation and scatter. Experiments were completed to show the quantification algorithm produces linear results from 0.03 uCi/mL to 30 uCi/mL. Additionally, further investigation into the potential of imaging the radioactive rpFNA needles with our current semiconductor camera revealed that it was not likely the needles would contain enough radioactivity to be distinguished above background. Work resulting from this project was presented at a local seminar and international conference this year and several manuscripts are being submitted for peer review.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 2010
- Accession Number
- ADA524522
Entities
People
- Kristy L. Perez
Organizations
- Duke University