Dietary Heterocyclic Amines and Polymorphic Variants in the Etiology of Prostate Cancer

Abstract

This project explored the hypothesis that higher intake of dietary carcinogens (e.g. heterocyclic amines) was associated with elevated risk of prostate cancer. It also explored the potential that polymorphic variation in key metabolism genes may affect risk. The project conducted a case-control study on 392 cases and 342 controls. Biosamples were obtained on over 96% of participants. Initial analyses provide only limited support for our hypothesis, mostly "trends" without clear statistical significance.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2010
Accession Number
ADA525085

Entities

People

  • Nicholas Birkett

Organizations

  • University of Ottawa

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Boundaries
  • Cancer
  • Carcinogens
  • Computer Programs
  • Databases
  • Etiology
  • Health Services
  • Medical Personnel
  • Neoplasms
  • Physicians
  • Pilot Studies
  • Prostate
  • Prostate Cancer
  • Public Health
  • Vitamin D

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