Evaluation of RSDL, M291 SDK, 0.5% Bleach, 1% Soapy Water and SERPACWA. Part 1: Challenge with VX

Abstract

There is a need for Joint forces to effectively operate across the continuum of global contingency operations. The requirement exists for a pre-exposure barrier skin cream to increase the efficacy of the protective suit and for the ability to decontaminate the skin, individual equipment, and casualties, including those with wounds that have been exposed to chemical, biological, radiological, and nuclear (CBRN) warfare agents. Current doctrine describes the use of Skin Exposure Reduction Paste Against Chemical Warfare Agents (SERPACWA) as a barrier skin cream and the M291 Skin Decontamination Kit (SDK), 0.5% hypochlorite solution (household bleach diluted 1 to 10) and 1% soapy water solution to decontaminate intact skin exposed to chemical warfare agents. Reactive Skin Decontamination Lotion (RSDL) is a new product approved by the FDA and selected in March 2007 by the Joint Program Executive Office for Chemical and Biological Defense to eventually replace the M291 SDK. This report, the first in a series, directly compares the efficacy of SERPACWA and the four listed decontamination products in the haired guinea pig model following exposure to VX.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2009
Accession Number
ADA525186

Entities

People

  • Bryce F. Doxzon
  • Edward D. Clarkson
  • Ernest H. Braue Jr.
  • Horace K. Lumpkin
  • Kelly A. Hanssen

Organizations

  • United States Army Medical Research Institute of Chemical Defense

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Casualties
  • Chemical Warfare
  • Chemical Warfare Agents
  • Chemical Weapons
  • Chlorides
  • Data Sets
  • Decontamination Kits
  • Executives
  • Factor Analysis
  • Families (Human)
  • Information Science
  • Laboratory Animals
  • Medical Personnel
  • Military Medicine
  • Nerve Agents
  • Rodents

Readers

  • Critical Infrastructure Protection in CBRN and WMD Threats.
  • Environmental Engineering.
  • Toxicology/Environmental Toxicology