A Randomized Placebo-Controlled Trial of D-Cycloserine for the Enhancement of Social Skills Training in Pervasive Development Disorders
Abstract
The main objective of this application is to determine whether D-cycloserine (DCS) can enhance the efficacy of social skills training (SST) in the treatment of children and young adolescents with autism. We will evaluate the efficacy, tolerability, and lasting effects of DCS given one hour prior to each of 10 weekly SST sessions for the treatment of social impairment in 52 children and young adolescents (ages 7-14 years) with PDDs during a randomized placebo-controlled trial. The safety and tolerability of DCS and durability of treatment response will also be examined. Institutional IRB and Department of Defense Human Research Protections Office approval have been obtained. Staff have been hired and trained on study procedures. Supplies have been purchased. Children participating in the first group have been screened and will begin on March 30, 2010
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 2010
- Accession Number
- ADA527641
Entities
People
- Gary W. Miller
Organizations
- Indiana University Health