Ocular Safety of Topical Naltrexone

Abstract

Dr. Sassani and his associates have been funded to perform a Phase I Clinical Trial of Naltrexone dissolved in Vigamox (R) and applied topically as eye drops preliminary to a therapeutic trial of that medication in the treatment of corneal epithelial defects in diabetic individuals. During the past year, we have obtained Institutional Review Board approval from the Hershey medical Center and the DOD. This approval required more time than anticipated, probably because this is the first time that Naltrexone has been applied topically to the eye even though it is approved for systemic use for other purposes.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 2010
Accession Number
ADA527744

Entities

People

  • Joseph W. Sassani

Organizations

  • Pennsylvania State University

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Cell Division
  • Cells
  • Clinical Trials
  • Department Of Defense
  • Epithelial Cells
  • Growth Factors
  • Institutional Review Board
  • Pennsylvania
  • Peptides
  • Recruiting
  • Side Effects
  • Universities
  • Wound Healing

Fields of Study

  • Medicine

Readers

  • Clinical Trial Research.
  • Neurotrauma and Rehabilitation Medicine.