Early Support of Intracranial Perfusion
Abstract
This report represents the third year in a multi-year effort to improve outcomes in patients with traumatic brain injury (TBI) utilizing human and animal models. Year 1 focused on development of an infrastructure for gathering data in TBI patients, development of a protocol to advance understanding of the inflammatory process which follows TBI, and creation of a basic science model of brain trauma. Staff were hired and assigned, equipment purchased and protocols and databases developed. Year 2 saw the implementation of two human use protocols, on-going development and testing of the Brain Resuscitation Registry (BRR) to provide structure and linkage capabilities for data collection and outcome reporting, and further development and reformatting of the animal model sub-project. Year 3 accomplishments included the ongoing enrollment of subjects in the human use protocols, development and implementation of 2 retrospective human use protocols, processing of specimens for the Cytokines sub-project, further development of the BRR and initiation of the basic science model including both small and large animal models of poly trauma. A one-year no-cost extension was granted in August 2010. This extension will allow completion of the current protocols as well as addition of 1 new human use protocol.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2010
- Accession Number
- ADA531861
Entities
People
- Thomas Scalea
Organizations
- University of Maryland, Baltimore