X-Ray Phase Imaging for Breast Cancer Detection

Abstract

The long term objective of the project is to develop a low-dose and quantitative phase x-ray imaging technique for facilitating breast cancer detection. In this period we have accomplished following tasks: (1) We refined the attenuation-partition based phase retrieval method for speeding up the iteration convergence, and systematically and quantitatively compared its performance against that of the mostly used phase retrieval method (the TIE method). A digital breast lumpectomy specimen model was constructed for facilitating the quantitative evaluations. We showed that the attenuation-partition based phase retrieval method is much more robust against image noise and the alignment errors than the TIE method does. (2) The system hardware integration has been completed in this period. The tests showed that the system is functioning for phase contrast image acquisition with high energy x-rays. The efforts for technique optimization are under the way.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2010
Accession Number
ADA535309

Entities

People

  • Xizeng Wu

Organizations

  • University of Alabama

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acquisition
  • Breast Cancer
  • Detection
  • Detectors
  • Diagnostic Imaging
  • Diffraction
  • Electrons
  • Health Services
  • High Energy
  • Imaging Techniques
  • Neoplasms
  • Optics
  • Radiography
  • Tomography
  • Two Dimensional
  • X Rays
  • X-Ray Computed Tomography

Fields of Study

  • Physics

Readers

  • Medical Imaging.
  • Systems Analysis and Design