A Novel Approach for the Identification of Pharmacophores Through Differential Toxicity Analysis of Estrogen Receptor Positive and Negative Cell Lines
Abstract
This grant was awarded to the PI at Louisiana State University. He left there in Aug 2006 and with Dr. Carole Christian, it was transferred to the University of Louisville. Minimal work was done on the project prior to departure from LSU and minimal funds were expended. The PI's new laboratory has been equipped with the needed computer hardware and software and a postdoctoral fellow (C. Alex Carrasquer) and research associate (Shahid Qamar) work on this project. Briefly, Aim 1 is essentially completed and several publications are in preparation, results for Aim 2 have also been generated, and in conjunction with Aims 1 and 2, a list of compounds for in vitro testing in Aim 3 have been forwarded to the project's collaborator Dr. Billy Day at the University of Pittsburgh. Dr. Day is currently working on getting physical samples from the NCI for testing, has established the protocols for his aim, has published several manuscripts related to this project, and his graduate student Miranda Sarachine, partially funded by this project, has graduated with a Ph.D.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2009
- Accession Number
- ADA538258
Entities
People
- Albert R. Cunningham
Organizations
- University of Louisville