Non-Invasive Nanodiagnostics of Cancer (NINOC)

Abstract

This project seeks to develop noninvasive diagnostics to detect cancer in its earliest, most easily treatable, pre-symptomatic stage. Innovative imaging nanomaterials and delivery technologies are employed to target, label, and detect the cancer cells within the body at sites which are normally inaccessible to conventional diagnostic methods. The hydrophilic polymer nanogels of core-shell emission computed tomography, computer tomography, magnetic resonance, or luminescence detection. The surface of the nanogels is modified with genetically engineered antibody fragments to target the surface of cancer cells and provide site-specific delivery of the nanogels to tumors in the body.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 2010
Accession Number
ADA538260

Entities

People

  • Alexander Kabanov

Organizations

  • University of Nebraska Omaha

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Biomedical Research
  • Block Copolymers
  • Chemical Synthesis
  • Chemistry
  • Colon Cancer
  • Imines
  • Magnetic Resonance
  • Materials
  • Measurement
  • Nanomaterials
  • Organic Chemistry
  • Particle Size
  • Polymers
  • Proteins
  • Resonance
  • Surface Plasmon Resonance

Fields of Study

  • Physics

Readers

  • Canadian European Scientific Immigration and Epilepsy Clearance Studies
  • Nanoscale Plasmonic Nanotechnology
  • Oncology (Cancer Research).

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech