Effects of Acute and Recurrent Stress During Adolescence on Subsequent Indices of Adult Behavioral Health in Rats
Abstract
The current research was designed to examine the effects of acute and recurrent stress during late adolescence on subsequent indices of adult behavioral health. The research used an animal (rat) model to examine four specific aims: (1) determine how repeated acute predator stress during adolescence affects behavioral indices of anxiety, depression, and alcohol consumption during adulthood; (2) evaluate how recurrent sleep disruption during adolescence affects behavioral indices of anxiety, depression, and alcohol consumption during adulthood; (3) evaluate the combined effects of predator stress and sleep disruption during adolescence on behavioral indices of anxiety depression, and alcohol consumption during adulthood; (4) evaluate genetic and sex differences in the stress effects during adolescence on adult behavioral indices of anxiety, depression, and alcohol consumption during adulthood in male and female rats of two different strains (genotypes).
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 10, 2009
- Accession Number
- ADA539651
Entities
People
- Michael E. Perry
Organizations
- Uniformed Services University of the Health Sciences