The Analysis of Cyanide and Its Breakdown Products in Biological Samples

Abstract

Cyanide is a toxic chemical that may be introduced into living organisms as a result of natural processes and/or anthropogenic uses (legal or illicit). Exposure to cyanide can be verified by analysis of cyanide or one of its breakdown products from biological samples. This verification may be important for medical, law-enforcement, military, forensic, research, or veterinary purposes. This review will discuss current bioanalytical techniques used for the verification of cyanide exposure, identify common problems associated with the analysis of cyanide and its biological breakdown products, and briefly address the metabolism and toxicokinetics of cyanide and its breakdown products in biological systems.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2010
Accession Number
ADA539827

Entities

People

  • Brian A Logue
  • Diane M. Hinkens
  • Gary A. Rockwood
  • Steven I. Baskin

Organizations

  • United States Army Medical Research Institute of Chemical Defense

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood
  • Chemical Synthesis
  • Chemistry
  • Cyanides
  • Detection
  • Fish
  • Health Services
  • Imines
  • Liquid Chromatography
  • Mass Spectrometry
  • Medical Personnel
  • Organic Chemistry
  • Spectrometry

Readers

  • Analytical Chemistry
  • Systems Analysis and Design
  • Toxicology/Environmental Toxicology