Photonic Breast Tomography and Tumor Aggressiveness Assessment
Abstract
The tasks performed and the progresses made during the current reporting period include: (a) pursuing planned training objectives of the researchers from the City College of New York (CCNY) through attending courses and seminars at the memorial Sloan Kettering Cancer Center (MSKCC); and (b) conducting research on development of non-invasive optical imaging and spectroscopic approaches for breast tumor detection. The CCNY researchers took five courses in the areas of cancer biology, biochemistry, genetics, and pharmacology and attended a molecular imaging seminar series and journal clubs to develop sound background in the biological and clinical aspects of cancer research. The research component involved application and further refinement of optical tomographic imaging using independent component analysis (OPTICA) for locating and cross-section imaging of a tumor in a model cancerous breast assembled using ex vivo breast tissue specimens. The OPTICA approach was able to detect, provide the location with an accuracy of ~ 1 mm and cross section of the tumor in the model cancerous breast.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2008
- Accession Number
- ADA540680
Entities
People
- F. B. Lin
- J. A. Koutcher
- R. R. Alfano
- S. K. Gayen
Organizations
- New York University