Hierarchical and Multiscale Modeling for Elucidating the Androgren Receptor Signaling Pathway in Prostate Cancer

Abstract

Developed a method for multiscale analysis of genomic data. This method can be used to decompose high-throughput gene expression into natural clusters at different scales or resolution, thereby facilitating models that can interrogate disease using molecular profiling.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2009
Accession Number
ADA541199

Entities

People

  • Justin Guinney

Organizations

  • Duke University

Tags

DTIC Thesaurus Topics

  • Biological Sciences
  • Biology
  • Cell Physiological Processes
  • Computational Biology
  • Computational Science
  • Diseases And Disorders
  • Earth Sciences
  • Eigenvectors
  • Gene Expression
  • Genetics
  • Materials
  • Multiscale Models
  • Neoplasms
  • Probability
  • Prostate
  • Prostate Cancer
  • Proteins

Fields of Study

  • Biology
  • Chemistry

Readers

  • Computational Fluid Dynamics (CFD)
  • Molecular Biology and Genetics
  • Molecular Genetics