Closed-Loop Resuscitation of Hemorrhagic Shock
Abstract
Our goal was to deliver a clinical solution to fluid resuscitation for combat casualties in the absence of advanced caregivers. We developed the Trauma Tablet Decision Support (DS), the first of a new breed of smart medical devices that provides caregivers with decision support using algorithms developed based on TCCC guidelines, expert opinion and resuscitation research. Trauma Tablet DS integrates a vital signs monitor, IV pump, and resuscitation algorithms controlled from a fat finger touch screen. We submitted an application for an FDA 510K allowance of Trauma Tablet DS, which incorporated QNX OS, a military spec Panasonic Toughbook, an eQuality Criticare Monitor, and a Zoll IV Pump. The FDA response had addressable issues with the response being developed by Arcos, the licensee of this technology. Trauma Tablet Closed Loop (CL) has been designed to provide automated titrated fluid therapy. The closed loop algorithms were developed and tested using the Impact LTM, and will be commercialized in the Trauma Tablet CL. The decision support and closed algorithms were tested in human subjects, and was shown to be robust and effective. Work effort on this project has transitioned from UTMB research and development to Arcos for advanced prototyping, regulatory approval, and commercialization, and to Dr. Mike Kinsky for clinical testing.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 21, 2011
- Accession Number
- ADA542181
Entities
People
- George C. Kramer
Organizations
- University of Texas Medical Branch