A Fresh Approach to Identification and Characterization of Early Changes of Disease Associated with Ovarian Cancer
Abstract
Our Consortium Development Award allowed us to bring together researchers from MD Anderson, Weizmann Institute, Lawrence Berkley National Labs, Harvard Medical Center, Baylor College of Medicine, Imperial College, Norway Radium Hospital and the University of Toronto in a series of face to face meeting and teleconferences. In this last year, we have consolidated our ovarian data from the various institutions into a centralized database and have added external data only recently available from the TCGA. This has allowed us to develop a strategy on how we can best utilize the talents of our consortium members to address the early molecular changes in ovarian cancer. Based on new data and most importantly input from our consortium members, we will focus our efforts on the early events leading to HGS-OvCa. This is most critical challenge in ovarian cancer as HGS-OvCa constitutes 70% of the cases and 85% from ovarian cancer. Further less is known about the events leading to initiation and progression of HGS-OvCa with even the cell of origin of HGS OvCa.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 2011
- Accession Number
- ADA542288
Entities
People
- Gordon B. Mills
Organizations
- The University of Texas MD Anderson Cancer Center