Nanotechnology-Enabled Optical Molecular Imaging of Breast Cancer

Abstract

This project focuses on development of nanotechnology-enabled optical molecular imaging technologies for applications in both breast cancer diagnosis and monitoring therapeutic response. The project consists of two major efforts: (1) optical instrumentation technology development and (2) development of complementary engineered nanomaterials for use in conjunction with the instrumentation created to provide molecular specificity. A particularly significant effort is underway to develop a needle-compatible fiber optic probe to enable in vivo imaging of tumors with micron resolution in order to provide a new microscopic, high resolution imaging modality to complement the low resolution, macroscopic imaging modalities already in common clinical use. An initial journal publication describing the single fiber needle-compatible microendoscope was recently accepted and a provisional patent application was filed on this technology during the most recent reporting period.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2010
Accession Number
ADA542313

Entities

People

  • Rebekah Drezek

Organizations

  • Rice University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Breast Cancer
  • Cells
  • Cellular Structures
  • Chemical Synthesis
  • Chemistry
  • Health Services
  • High Resolution
  • Materials
  • Materials Science
  • Medical Personnel
  • Metallic Nanoparticles
  • Nanotechnology
  • Optical Properties
  • Optics
  • Patent Applications
  • Surface Plasmon Resonance

Fields of Study

  • Medicine
  • Physics

Readers

  • Medical Imaging.
  • Optical Fiber Sensing and Electromagnetic Propagation.
  • Technical Research and Report Writing.

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech