Triterpenoidal Saponins: Bioactive Secondary Metabolites from Zygophyllum coccineum

Abstract

Phytochemical investigation of the aerial parts of Zygophyllum coccineum L. led to the isolation of nine ursane-type triterpene saponins, including the new one; zygophylloside S, together with a known flavonoid glycoside and a sterol glycoside. The isolated compounds were tested for antifungal activity against several important plant pathogens and for insecticidal activity against two important mosquito species. Among the isolated compounds 1, 3, 5, 6, and 9 showed 32-77% fungal growth inhibition at a concentration of 30 microns against Phomopsis viticola. Compound 9 showed 90% and 80% mosquitocidal activity at 3.1 micrograms/0.5 microlitters against Aedes aegypti and Culex quinquefasciatus, respectively.

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Document Details

Document Type
Technical Report
Publication Date
Jan 22, 2011
Accession Number
ADA545435

Entities

People

  • David E. Wedge
  • Elham Amin
  • Ikhlas A. Khan
  • James John Becnel
  • Magda M. Fathy
  • Nurhayat Tabanca
  • Rabab Mohammed
  • Seham S. El-hawary
  • Zulfiqar Ali

Organizations

  • Agricultural Research Service

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Acetic Acid
  • Antifungal Agents
  • Assays
  • Bioassay
  • Biological Products
  • Column Chromatography
  • Fungi
  • Glycosides
  • Health Services
  • Inhibition
  • Metabolites
  • New York
  • Particle Size
  • Pest Control
  • Pharmacies
  • Silica Gels
  • Terpenes

Fields of Study

  • Agricultural and Food sciences

Readers

  • Analytical Chemistry
  • Vector-Borne Disease and Entomology