The Association of Valproic Acid and Incident Breast Cancer in a Managed Care Cohort

Abstract

The possible role of histone deacetylase inhibitors (HDACi) in breast cancer treatment is an area of active investigation. However, its potential as a preventive agent has not been studied. Valproic acid (VPA) is an HDACi which has been used for many decades to safely treat neurological disorders. The rationale for the use of HDACi in breast cancer prevention is a previously unexplored area of research that is based on compelling preclinical data.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2010
Accession Number
ADA546714

Entities

People

  • Eun-sil S. Hwang

Organizations

  • University of California, San Francisco

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Anticonvulsants
  • Biomedical Research
  • Breast Cancer
  • Department Of Defense
  • Diseases And Disorders
  • Electronic Mail
  • Enzyme Inhibitors
  • Governments
  • Information Operations
  • Instructions
  • Maryland
  • National Governments
  • Neoplasms

Fields of Study

  • Medicine

Readers

  • Facility/Structural Engineering.
  • Molecular and Cellular Biology
  • Oncology (Cancer Research).