Ultrasound-Based Guidance for Partial Breast Irradiation Therapy
Abstract
Tracked ultrasound elastography can be used for guidance in partial breast radiotherapy by visualizing the hard scar tissue around the lumpectomy cavity. For clinical success, the elastography method needs to be robust to the sources of decorrelation between ultrasound images, specifically fluid motions inside the cavity, change of the appearance of speckles caused by compression or physiologic motions, and out-of-plane motion of the probe. In this report, we extend our previous work where we proposed 1D Analytic Minimization (1D AM) of a cost function to calculate robust elasticity images to 2D AM. We show that 2D AM is much faster than 1D AM, which is critically important in creating real-time elastography. In addition, 2D AM produces high quality strain images in 2D which can be used for elasticity reconstruction using an inverse problem framework. We also propose a novel strain calculation technique using Kalman filters, which generates smooth strain images without blurring the images and removing sharp boundaries. We show using simulation, phantom and clinical trials that the 2D AM generates high quality strain images in real-time. This work is in press for IEEE TMI. We have also introduced a novel elastography technique, which uses multiple images to calculate elasticity image. A manuscript has been submitted to IEEE TMI.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 2011
- Accession Number
- ADA547590
Entities
People
- Hassan Rivaz
Organizations
- Johns Hopkins University