Development of Prior Image-Based, High-Quality, Low-Dose Kilovoltage Cone Beam CT for Use in Adaptive Radiotherapy of Prostate Cancer
Abstract
Adaptive radiotherapy (RT) is an advanced technique for prostate cancer treatment which employs kilovoltage (KV) cone-beam CT (CBCT) for guiding treatment. High quality CBCT images are important in achieving improved treatment effect, but they also require a non-negligible amount of imaging radiation dose which raises patient safety concern. Therefore, the goal of this project is to investigate and develop innovative, prior-image-based CBCT imaging techniques that can yield high quality images with reduced dose. During the first year of this project, I have focused on investigation and development of prior image-based, narrowly collimated CBCT imaging technique. I also started to investigate and develop total-variation-based image-reconstruction algorithms. In addition, I have designed and developed software utilities and hardware devices necessary for the proposed experiments. In summary, during the first year, I have successfully carried out research on the planned tasks, and the results obtained have formed a solid basis for me to continue the research planned for the next year.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 2011
- Accession Number
- ADA547607
Entities
People
- Xiao Han
Organizations
- University of Chicago