Integrative Functional Genomics and Proteomics to Uncover Mechanisms of Resistance to Chemotherapy in Ovarian Cancer

Abstract

Ovarian cancer affects approximately 22,000 women and kills approximately 16,000 women each year in the United States. Resistance to chemotherapy is the major contributing factor in ovarian cancer-related death. The primary objective of this study is to gain mechanistic insights into the development of chemotherapy resistance in ovarian cancer. We expect that advances in this study will contribute to our understanding of chemotherapy resistance in ovarian cancer and will facilitate the development of more effective therapies to overcome the problems of chemotherapy resistance.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2011
Accession Number
ADA548144

Entities

People

  • Jeremy Chien

Organizations

  • Mayo Clinic

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Cancer
  • Cell Line
  • Chemotherapy
  • Computational Biology
  • Costs
  • Department Of Defense
  • Gene Expression
  • Genetics
  • Genomics
  • Institutional Review Board
  • Neoplasms
  • Ovarian Cancer
  • Proteomics
  • Resistance
  • Therapy
  • United States

Readers

  • Oncology

Technology Areas

  • Biotechnology